The Gene: An Intimate History, by Siddhartha Mukherjee. His previous work on cancer, The Emperor of All Maladies, was one of the best medico-scientific books I've read in years.
You May Also Like: Taste in an Age of Endless Choice, by Tom Vanderbilt, author of Traffic: Why We Drive the Way We Do (and What It Says About Us).
Paper, by Mark Kurlansky, godfatherof the single-word-title-biography-of-a-substance book (Salt).
What else should I be reading? Tell me.